| 高效液相色谱法测定喘可治注射液中淫羊藿苷含量 |
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| 引用本文： | 姚虹,周淑琴,李瑾.高效液相色谱法测定喘可治注射液中淫羊藿苷含量[J].中国药业,2012,21(10):45-46. |
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| 作者姓名： | 姚虹 周淑琴 李瑾 |
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| 作者单位： | 上海医药高等专科学校药学系,上海,201318 |
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| 摘 要： | 目的 建立测定喘可治注射液中淫羊藿苷含量的高效液相色谱法.方法 采用Agilent TC -C18色谱柱(250 mm× 4.6 mm,5μm),流动相为乙腈-水(20∶80),检测波长为270 nm.结果 淫羊藿苷进样量的线性范围为1.62～4.32 μg,平均回收率为99.30％,RSD为1.13％(n=6).结论 该方法操作简便可行、重复性好,适用于喘可治注射液中淫羊藿苷的含量测定,可用于该制剂的质量控制.
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| 关 键 词： | 淫羊藿苷 喘可治注射液 高效液相色谱法 含量测定 |
Determination of Icariin in Chuankezhi Injection by HPLC |
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| Yao Hong
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Zhou Shuqin
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Li Jin.Determination of Icariin in Chuankezhi Injection by HPLC[J].China Pharmaceuticals,2012,21(10):45-46. |
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| Authors: | Yao Hong Zhou Shuqin Li Jin |
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| Institution: | ( Department of Pharmacy, Shanghai Institute of Health Sciences, Shanghai, China 201318) |
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| Abstract: | Objective To develop a HPLC method for determining the icariin content in Chuankezhi Injection. Methods The analysis was carried out on the Agilent TC-C18 column （250 mm ×4. 6 ram,5 μm）,with the mobile phase of acetonitrile-water（20：80） and the detection wavelength of 270 nm. Results The linear range of ieariin was 1, 62- 4. 32μg. The average recovery rate was 99.30% with RSD of 1.13% （n =6）. Conclusion The HPLC method is simple, feasible, repeatable and suitable for determining the icariin content and controlling the quality of this preparation. |
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| Keywords: | ieariin Chuankezhi Injection HPLC content determination |
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