| 5种中药注射液与输液配伍前后不溶性微粒变化 |
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| 引用本文： | 吴秀荣,林焕泽,李桃,杨华,黄群,蓝忠,陈建华.5种中药注射液与输液配伍前后不溶性微粒变化[J].中国药业,2012,21(7):6-7. |
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| 作者姓名： | 吴秀荣 林焕泽 李桃 杨华 黄群 蓝忠 陈建华 |
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| 作者单位： | 广东省茂名市人民医院药剂科,广东茂名,525000 |
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| 基金项目： | 广东省茂名市科技基地项目,项目编号：20092001. |
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| 摘 要： | 目的 考察5种中药注射液与葡萄糖大输液配伍后不溶性微粒数量的变化.方法 用微粒分析仪分别测定配伍前输液(5%葡萄糖注射液)及其与中药注射液(血塞通注射液、银杏达莫注射液、红花注射液、参附注射液、香丹注射液)配伍后的微粒数目,并考察配伍后不同时间测得的微粒数.结果 输液中不溶性微粒数显著多于配伍前(P<0.01或P<0.05).结论 输液与中药注射液配伍后微粒数目明显增多,在临床应用中应重视此现象,尽量避免药品不良反应的发生.
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| 关 键 词： | 中药注射液 输液 不溶性微粒 |
Changes of Insoluble Particles in 5 Kinds of Traditional Chinese Medicine Injections Mixed with Infusion Solution |
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| Wu Xiurong
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Lin Huanze
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Li Tao
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Yang Hua
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Huang Qun
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Lan Zhong
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Chen Jianhua.Changes of Insoluble Particles in 5 Kinds of Traditional Chinese Medicine Injections Mixed with Infusion Solution[J].China Pharmaceuticals,2012,21(7):6-7. |
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| Authors: | Wu Xiurong Lin Huanze Li Tao Yang Hua Huang Qun Lan Zhong Chen Jianhua |
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| Institution: | (Department of Pharmacy, Maoming People＇s Hospital, Maoming, Guangdong, China 525000) |
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| Abstract: | Objective To study the changes of the insoluble panicles in glucose injection（5% ） and in the glucose injections mixed with 5 different Chinese herbal IV injections. Methods Counted the number of insoluble particles in glucose injection（5% ） and in the glu- cose injections mixed with 5 different Chinese herbal IV injections,and investigated the number of insoluble panicles in the 5 injec- tions at different times. Results The numbers of insoluble particles obviously increased after combination（ P 〈 0.01 or P 〈 0.05）. Conclusion The increase of insoluble particles in these 5 Chinese herbal IV injections should be focused during clinical use. So the adverse reactions can avoid as far as possible. |
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| Keywords: | Chinese herbal IV injection injection insoluble particle |
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