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痰热清注射液与注射用头孢哌酮钠的配伍稳定性考察
引用本文:郝文耀,庆格乐,马小平,齐卫红.痰热清注射液与注射用头孢哌酮钠的配伍稳定性考察[J].中国药业,2012,21(10):23-24.
作者姓名:郝文耀  庆格乐  马小平  齐卫红
作者单位:1. 武警内蒙古总队医院药剂科,内蒙古呼和浩特,010040
2. 内蒙古呼和浩特市药品检验所,内蒙古呼和浩特,010020
摘    要:目的 考察痰热清注射液与注射用头孢哌酮钠在0.9%氯化钠注射液中的配伍稳定性.方法 在室温(25℃)下采用紫外分光光度法测定痰热清注射液和注射用头孢哌酮钠在0.9%氯化钠注射液中配伍6h内不同时间点的含量,并观察配伍液的外观、微粒及pH变化.结果 两药配伍后6h内的含量、pH、外观及不溶性微粒均无明显变化.结论 痰热清注射液与注射用头孢哌酮钠在0.9%氯化钠注射液中配伍后于室温下6h内可使用.

关 键 词:痰热清注射液  注射用头孢哌酮钠  配伍  稳定性  紫外分光光度法

Compatible Stability of Tanreqing Injection Admixed with Cefoperazone Sodium for Injection
Hao Wenyao , Qing Gele , Ma Xiaoping , Qi Weihong.Compatible Stability of Tanreqing Injection Admixed with Cefoperazone Sodium for Injection[J].China Pharmaceuticals,2012,21(10):23-24.
Authors:Hao Wenyao  Qing Gele  Ma Xiaoping  Qi Weihong
Institution:1. Department of Pharmacy, Neimenggu Corps Hospital, Armed Police Force, Huhehaote, Neimenggu, China 010040; 2. Huhehaote Municipal Institute for Drug Control, Huhehaote, Neimenggu, China 010020)
Abstract:Objective To study the compatible stability of Tanreqing Injection admixed with cefoperazone sodium for injection in 0.9% sodium chloride injection. Methods The content of the mixture in 0.9% sodium chloride injection at different time points were de- termined by UV spectrophotometry. Meanwhile,the changes of appearance, particles and pH value of the solution were observed at the room temperature(25 ℃ )within 6 h. Results No significant differences were noted in the content,appearance and pH value for the com- patible solution within 6 h at room temperature. Conclusion The mixture of Tanreqing Injection and cefoperazone sodium for injection in 0.9% sodium chloride injection can be mixed to use within 6 h under the room temperature.
Keywords:Tanreqing Injection  cefoperazone sodium  compatibility  stability  UV spectrophotometry
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