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医院抗骨质疏松药物用药趋势分析与合理应用评价
引用本文:尹月,邱新野,高振梅,刘泽源. 医院抗骨质疏松药物用药趋势分析与合理应用评价[J]. 中国药业, 2012, 21(7): 26-29
作者姓名:尹月  邱新野  高振梅  刘泽源
作者单位:1. 军事医学科学院附属医院药学部,北京,100071
2. 首都医科大学附属北京佑安医院药学中心,北京,100069
摘    要:目的 分析医院抗骨质疏松药的应用情况,为临床合理使用提供参考.方法 根据抗骨质疏松药的不同结构及作用机制进行分类,采用世界卫生组织推荐的限定日剂量、用药频度分析法对2008年至2010年抗骨质疏松药销售金额、用药频度及日均费用等进行回顾性分析.结果 抗骨质疏松药中,碳酸钙片迪巧于和钙尔奇-D用药频度最高,双膦酸盐类增长迅速;唑来磷酸(择泰)日均费用最高.结论 抗骨质疏松药物应用情况调查,对于促进合理应用及临床监护具有重要意义.

关 键 词:抗骨质疏松药  药物利用分析  合理用药

Trend Analysis on Anti-Osteoporosis Drugs Use in Our Hospital and Reasonable Application Evaluation
Yin Yue , Qiu Xinye , Gao Zhenmei , Liu Zeyuan. Trend Analysis on Anti-Osteoporosis Drugs Use in Our Hospital and Reasonable Application Evaluation[J]. China Pharmaceuticals, 2012, 21(7): 26-29
Authors:Yin Yue    Qiu Xinye    Gao Zhenmei    Liu Zeyuan
Affiliation:1. Department of Pharmacy, Affiliated Hospital, Academy of Military Medical Sciences, Beijing, China 100071; 2. Pharmacy Center, AJliated Youan Hospital, Capital Medical University, Beijing, China 100069)
Abstract:Objective To understand the use status of anti- osteoporosis drugs in our hospital to provide reference for clinical rational use. Methods The classification was conducted according to different structures and mechanisms of anti- osteoporosis drugs. The defined daily dose(DDD) frequency analysis recommended by WHO was adopted to retrospectively analyze the sale amounts, use frequency and daily drug costs of anti- osteoporosis drugs in our hospital from August 2008 to July 2010. Results Among anti- osteoporosis drugs, Calcium Carbonate Tablets, D- Cal and Caltrate- D had highest DDDs. Bisphosphonates were increased rapidly. Zometa had highest aver- age daily costs. Conclusion The investigation of anti- osteoporosis drugs use has important significance to promote their rational use and clinical monitoring.
Keywords:anti- osteoporosis drugs  drug utilization analysis  reasonable use
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