| 益肺通络颗粒质量标准研究 |
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| 引用本文： | 杨励,左亚杰,鲁虹,曾建国.益肺通络颗粒质量标准研究[J].中国药业,2012,21(10):26-27. |
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| 作者姓名： | 杨励 左亚杰 鲁虹 曾建国 |
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| 作者单位： | 1. 湖南省长沙市中心医院,湖南长沙,410004
2. 湖南中医药大学附属第一医院,湖南长沙,410004 |
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| 基金项目： | 2011年度湖南省中医药科研计划重点课题资助项目,项目编号：201113. |
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| 摘 要： | 目的 建立益肺通络颗粒的质量标准.方法 采用薄层色谱法对方中黄精、紫花地丁、百部进行定性鉴别；采用高效液相色谱法对矮地茶的主要成分岩白菜素进行含量测定.结果 在薄层色谱中可检出黄精、紫花地丁、百部的特征斑点,且斑点清晰,易于观察；岩白菜素进样量在0.054～0.54μg范围内与峰面积线形关系良好(r=0.99906),平均回收率为98.54％,RSD为1.31％(n=6).结论 所用方法简便、准确、重现性好,可作为该制剂的质量控制方法.
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| 关 键 词： | 益肺通络颗粒 薄层色谱法 高效液相色谱法 质量标准 |
Study on Quality Standard for Yifei Tongluo Granules |
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| Yang Li
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Zuo Yajie
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Lu Hong
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Zeng Jianguo.Study on Quality Standard for Yifei Tongluo Granules[J].China Pharmaceuticals,2012,21(10):26-27. |
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| Authors: | Yang Li Zuo Yajie Lu Hong Zeng Jianguo |
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| Institution: | 1. Changsha Central Hospital, Changsha, Hunan, China 410004; 2. First Affiliated Hospital, Hunan University of Traditional Chinese Medicine, Chang- sha, Hunan, China 410004) |
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| Abstract: | Objective To establish the quality standard for Yifei Tongluo Granules. Methods Polygonati Rhizoma, Violae Herba and Stemonae Radix were qualitatively identified by the thin layer chromatography（TLC）. The content of bergeninum was determined by high performance liquid chromatography（HPLC）. Results The characteristic spots of Polygonati Rhizoma,Violae Herba and Stemonae Radix in TLC were clear and distinguished well. The linear range of bergeninum was 0.054-0.54 μg（r=0.999 06）.The average recovery rate was 98.54% with the RSD = 1.31% （n = 6）. Conclusion The method is simple, accurate and repeatable,which can be used for the quality control of Yifei Tongluo granules. |
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| Keywords: | Yifei Tongluo Granules TLC HPLC quality standard |
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