The effect of hydrophilic base on pharmaceutical availability of prednisolone complexed with beta-cyclodextrin |
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| Authors: | Szcze?niak Maria Kubis Aleksander A Pluta Janusz |
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| Institution: | Department of Pharmaceutical Technology, Wroc?aw Medical University. szczesniak@gmail.com |
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| Abstract: | Studies on the effect of hydrophilic gel composition on pharmaceutical availability of prednisolone complexed with beta-cyklodextrin at P:beta-CD ratios 1:1 and 1:2 revealed that the half-release times were shortened and differentiated depending on the substances added hydrogel to propylene glycol, dimethylacetamide and polysorbate 20 in comparison to preparations containing non-complexed active substance. |
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