Cardiac 123I-MIBG scintigraphy and arrhythmic risk in left ventricular noncompaction |
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Authors: | Oliveira Sílvia Marta Martins Elisabete Oliveira Ana Pinho Teresa Gavina Cristina Faria Teresa Silva-Cardoso José Carlos Pereira Jorge Maciel Maria Júlia |
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Affiliation: | Cardiology Department, Hospital de S?o Jo?o, Porto, Portugal. silviamartaoliveira@hotmail.com |
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Abstract: | Left ventricular noncompaction is an unusual but increasingly recognized cardiomyopathy, the etiology of which is still not definitely established. Clinical presentation includes a wide spectrum of scenarios, including heart failure, thromboembolism and malignant arrhythmias, with half of deaths occurring suddenly. Early detection of LVNC is therefore essential to prevent sudden cardiac death. To our knowledge, this is the first report of the presence of cardiac sympathetic nervous dysfunction, assessed by 123iodine-metaiodobenzylguanidine myocardial scintigraphy, in a patient with LVNC, preserved left ventricular systolic function and exercise-induced nonsustained ventricular tachycardia. This finding may be related to the increased arrhythmic risk observed in this cardiomyopathy, giving a new insight into the pathophysiology of LVNC. |
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