Correction by common sea buckthorn bark and sprout extracts of hormonal and metabolic disturbances during stress in rats

Long-term administration of the common sea buckthorn bark and sprout extract improves the hormonal-metabolic organism status in rats disturbed by a stress factor (immobilization). The drug administration led to normalization of the altered functional activity indices of the neuro-endocrine system (disturbed adrenocorticotropin, 11-deoxycortisol, insulin, urea, and glucose levels) by affecting the production of glucocorticoids and increasing the hypothalamus sensitivity with respect to regulatory signals.