Levarterenol bitartrate (levophed) in the treatment of cardiac arrhythmias |
| |
| Authors: | MCGINN J T SCHLUGER J |
| |
| Affiliation: | 1. Department of Anaesthesiology, University Hospitals Leuven, Leuven, Belgium;2. Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium;3. Department of Cardiac Surgery, University Hospitals Leuven, Leuven, Belgium;4. Department of Intensive Care Medicine, University Hospitals Leuven, Leuven, Belgium;5. Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium;6. Department of Public Health and Primary Care, KU Leuven, Leuven, Belgium;7. Leuven Biostatistics and Statistical Bioinformatics Centre (L-BioStat), KU Leuven, Leuven, Belgium;1. Department of Surgery, Johns Hopkins Hospital, Baltimore, Md;2. The Johns Hopkins Bayview Vascular and Endovascular Research Center, Baltimore, Md;3. Division of Vascular Surgery and Endovascular Therapy, Keck School of Medicine, University of Southern California, Los Angeles, Calif;4. Division of Vascular Surgery and Endovascular Therapy, Johns Hopkins Bayview Medical Center, Baltimore, Md;5. Vascular and Endovascular Surgery, UCSD Health System, San Diego, Calif;1. University of California San Francisco School of Medicine, Department of Surgery, San Francisco, CA, USA;2. Zuckerberg San Francisco General Hospital, Department of Surgery, San Francisco, CA, USA;1. University College London Hospital NHS Foundation Trust, London, UK;2. Northwick Park Hospital NHS Trust, London, UK |
| |
| Abstract: | - 1.1. Six cases of supraventricular paroxysmal tachycardia and one case of ventricular tachycardia are presented in which the administration of levarterenol intravenously caused termination of the attack. In one case of auricular flutter the rate was slowed temporarily but the abnormal rhythm persisted.
- 2.2. Administration of the drug was only successful when it elevated the blood pressure to approximately normal levels.
- 3.3. It is suggested that levarterenol acts in those cases in which it causes reversion to normal rhythm by elevating the blood pressure. This stimulates receptors in the aorta and carotid sinus, causing reflex stimulation of the vagus. The profound vagal stimulation thus induced causes cessation of the attack.
|
| |
| Keywords: | |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ |
|
