代谢综合征与肾结石关系的研究进展

 肾结石是泌尿外科常见病,其患病率增长迅速。近些年的研究显示代谢综合征(metabolic syndrome,MS)与肾结石的形成和复发相关。代谢综合征包括高血压、糖尿病、肥胖等。24 h尿液分析是肾结石患者代谢评估的主要依据。近年来研究发现代谢综合征患者尿液中钙、枸橼酸盐、尿酸、草酸盐、磷酸盐以及蛋白等改变与肾结石形成和复发相关,而胰岛素抵抗在其中起重要作用。

Research advances in the association of metabolic syndrome with nephrolithiasis

Nephrolithiasis is a common urologic disease, of which the prevalence has been increasing rapidly.Recent studies have shown that metabolic syndrome(MS) is associated with the formation and recurrence of nephrolithiasis.Metabolic syndrome includes hypertension,diabetes, obesity and so on. 24-hour urinalysis is the main basis of the metabolic evaluation of patients with nephrolithiasis. Recently, it has been reported that changes in calcium, citrate, uric acid, oxalate, phosphate and protein in the urine of patients with metabolic syndrome are related to the formation and recurrence of nephrolithiasis, in which insulin resistance plays an important role.