Nocardiosis Causing Hypocellular Bone Marrow after Allogeneic Peripheral Blood Stem Cell Transplantation |
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Authors: | SAW Fadilah SK Cheong AA Raymond S Norlela |
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Institution: | 1. Division of Hematology and Stem cell transplantation Universiti Kebangsaan Malaysia (UKM), Kuala Lumpur, Malaysiasfadilah@mail.hukm.ukm.my;3. Division of Hematology and Stem cell transplantation Universiti Kebangsaan Malaysia (UKM), Kuala Lumpur, Malaysia;4. Division of Neurology, Faculty of Medicine, Universiti Kebangsaan Malaysia (UKM), Kuala Lumpur, Malaysia |
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Abstract: | Nocardia infection is rare in bone marrow transplant (BMT) recipients with less than 30 cases reported in the literature 1–4]. The majority of the cases occurred late in the post-transplant period. Common clinical presentations included formation of widespread and multiple abscesses. Bone marrow hypoplasia is an uncommon finding. We describe the first case of nocardiosis, diagnosed at day 100 after non-myeloablative allogeneic peripheral blood stem cell transplantation, presenting as pancytopenia and hypocellular marrow. Eradication of the infection with antibiotics resulted in complete hematological recovery. |
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Keywords: | Nocardiosis Bone marrow transplantation (BMT) Peripheral blood stem cell transplantation (PBSCT) Non-myeloablative Hypocellular marrow |
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