| Urocortin介导的对心脏保护作用的调节及针灸效应的研究分析 |
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| 引用本文： | 周传龙,包洁,邵晓梅,方剑乔,陈勤.Urocortin介导的对心脏保护作用的调节及针灸效应的研究分析[J].中华中医药学刊,2019(3):568-571. |
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| 作者姓名： | 周传龙 包洁 邵晓梅 方剑乔 陈勤 |
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| 作者单位： | 1.浙江中医药大学附属第三医院;2.浙江中医药大学第三临床医学院针灸教研室;3.浙江中医药大学 |
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| 基金项目： | 国家自然科学基金青年科学基金项目(81503643);浙江省中医药优秀青年人才基金项目(2015ZQ021) |
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| 摘 要： | 在心肌缺血损伤过程中,心脏保护因子Urocortin(Ucn)可以通过cAMP/PKA、PI3K-Akt、CaMKII、NO-cGMP、MAPK等多条信号通路进行干预,而在这个过程中介入针灸疗法同样可以通过这些途径对心肌进行保护,而且多条信号通路可以相互影响,机制非常复杂。就Ucn与针灸对缺血心肌在信号通路方面的保护机制进行归纳总结分析,以期为进一步探讨针灸对心脏保护的机制研究以及临床应用提供更广阔的思路。
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| 关 键 词： | 针灸 UROCORTIN 心脏保护 信号通路 |
Analysis of Heart Protection Mediated by Urocortin and Acupuncture Therapy |
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| ZHOU Chuanlong,BAO Jie,SHAO Xiaomei,FANG Jianqiao,CHEN Qin.Analysis of Heart Protection Mediated by Urocortin and Acupuncture Therapy[J].Chinese Archives of Traditional Chinese Medicine,2019(3):568-571. |
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| Authors: | ZHOU Chuanlong BAO Jie SHAO Xiaomei FANG Jianqiao CHEN Qin |
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| Institution: | (The Third Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310053 , Zhejiang,China;Institute of Acupuncture and Moxibustion ,The 3rd Clinical Medical College of Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang,China;Zhejiang Chinese Medical University, Hangzhou 310053 , Zhejiang,China) |
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| Abstract: | ZHOU Chuanlong;BAO Jie;SHAO Xiaomei;FANG Jianqiao;CHEN Qin(The Third Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310053 , Zhejiang,China;Institute of Acupuncture and Moxibustion ,The 3rd Clinical Medical College of Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang,China;Zhejiang Chinese Medical University, Hangzhou 310053 , Zhejiang,China) |
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| Keywords: | acupuncture Urocortin heart protection signal pathways |
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