| 丹红注射液联合脑心通胶囊对不稳定型心绞痛临床疗效及内皮功能影响的随机对照研究 |
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| 引用本文： | 唐咏,赵帅,侯乐,陈伯钧,侯开放.丹红注射液联合脑心通胶囊对不稳定型心绞痛临床疗效及内皮功能影响的随机对照研究[J].中华中医药学刊,2019(5):1231-1233. |
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| 作者姓名： | 唐咏 赵帅 侯乐 陈伯钧 侯开放 |
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| 作者单位： | 1.广州中医药大学第三附属医院内科;2.广州中医药大学第二附属医院急诊科;3.广州市惠爱医院内科;4.江门市五邑中医院内科 |
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| 基金项目： | 广东省中医药局一般项目(20171141) |
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| 摘 要： | 目的:采用随机对照盲法的研究设计方法,应用丹红注射液联合脑心通胶囊干预不稳定型心绞痛(UA)患者,观察其临床疗效及对血管内皮功能的影响。方法:治疗组和对照组均采用西医常规治疗,治疗组在此基础上,予静滴丹红注射液及口服脑心通胶囊;对照组在此基础上,予静滴葡萄糖注射液及口服安慰剂胶囊。结果:完成疗程后,治疗组的临床疗效明显优于对照组(P<0.05);治疗组更能改善血管内皮功能:治疗组NO水平上升较对照组更为明显(P<0.05),治疗组ET-1水平下降较对照组更为明显(P<0.05),治疗组vWF水平下降较对照组更为明显(P<0.05)。两组患者在治疗后均未发现不良反应。结论:通过本研究,发现丹红注射液联合脑心通胶囊可改善UA患者临床症状及内皮功能,无明显的不良反应,安全性较高,这为今后两药联合在临床应用的有效性与安全性提供更确切依据。
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| 关 键 词： | 不稳定型心绞痛 丹红注射液 脑心通胶囊 |
Study on Clinical Efficacy and Influence of Vascular Endothelial Function of Danhong Injection and Naoxintong Capsule for Unstable Angina:A Randomized Controlled and Double-Blind Trial |
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| TANG Yong,ZHAO Shuai,HOU Le,CHEN Bojun,HOU Kaifang.Study on Clinical Efficacy and Influence of Vascular Endothelial Function of Danhong Injection and Naoxintong Capsule for Unstable Angina:A Randomized Controlled and Double-Blind Trial[J].Chinese Archives of Traditional Chinese Medicine,2019(5):1231-1233. |
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| Authors: | TANG Yong ZHAO Shuai HOU Le CHEN Bojun HOU Kaifang |
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| Institution: | (The Third Affiliated Hospital of Guangzhou University of Chinese Medicine,Ghuangzhou 510360,Guangdong,China;The Second Affiliated Hospital of Guangzhou University of Chinese Medicine,Ghuangzhou 510120,Guangdong,China;Guangzhou Huiai Hospital,Ghuangzhou 510370,Guangdong,China;Wuyi Hospital of Traditional Chinese Medicine,Jiangmen 529000,Guangdong,China) |
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| Abstract: | TANG Yong;ZHAO Shuai;HOU Le;CHEN Bojun;HOU Kaifang(The Third Affiliated Hospital of Guangzhou University of Chinese Medicine,Ghuangzhou 510360,Guangdong,China;The Second Affiliated Hospital of Guangzhou University of Chinese Medicine,Ghuangzhou 510120,Guangdong,China;Guangzhou Huiai Hospital,Ghuangzhou 510370,Guangdong,China;Wuyi Hospital of Traditional Chinese Medicine,Jiangmen 529000,Guangdong,China) |
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| Keywords: | unstable angina Danhong Injection Naoxintong Capsule |
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