Synthesis,Antibacterial and Antitumor Activity of Semisynthetic Penicillins and Cephalosporins Based on New Sarcomycin Analogs |
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Authors: | A. O. Martirosyan S. P. Gasparyan V. E. Oganesyan V. V. Martirosyan A. A. Chachoyan E. V. Kazaryan B. T. Garibdzhanyan |
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Affiliation: | (1) Mndzhoyan Institute of Fine Organic Chemistry, National Academy of Sciences of the Republic of Armenia, Yerevan, Armenia |
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Abstract: | A series of new semisynthetic penicillins and cephalosporins containing structural fragments of the well-known antitumor antibiotic sarcomycin have been synthesized and their antitumor and antibacterial properties have been studied. The synthesized compounds showed substantial antitumor and antibacterial activities.__________Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 39, No. 2, pp. 13 – 15, February, 2005. |
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