Myokymia,neuromyotonia, dermatomyositis,and voltage-gated K+ channel antibodies |
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Authors: | Oh Shin J Alapati Anjaneyulu Claussen Gwen C Vernino Steven |
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Institution: | Department of Neurology, University of Alabama at Birmingham, UAB Station, Birmingham, Alabama 25294, USA. shinjoh@uab.edu |
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Abstract: | A young woman presented with facial myokymia in association with dermatomyositis. There was no evidence of peripheral neuropathy. Needle electromyography showed prominent myokymic discharges and brief neuromyotonic discharges in addition to many small-amplitude, short-duration motor unit potentials. Myokymia and dermatomyositis both responded to immunosuppressive treatment. The presence of antibodies to voltage-gated potassium channels and the association with dermatomyositis indicated an autoimmune cause for myokymia, which may have been due to reversible peripheral nerve hyperexcitability. |
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Keywords: | dermatomyositis Isaacs' syndrome myokymia neuromyotonia voltage‐gated K+ channel antibody |
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