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奥硝唑与甲硝唑治疗牙周炎疗效及副作用比较
引用本文:张丽莺,刘晓龙,高永珍,陈丽春. 奥硝唑与甲硝唑治疗牙周炎疗效及副作用比较[J]. 内蒙古医学杂志, 2006, 38(7): 591-592
作者姓名:张丽莺  刘晓龙  高永珍  陈丽春
作者单位:内蒙古自治区医院口腔科,内蒙古,呼和浩特,010017;内蒙古自治区医院口腔科,内蒙古,呼和浩特,010017;内蒙古自治区医院口腔科,内蒙古,呼和浩特,010017;内蒙古自治区医院口腔科,内蒙古,呼和浩特,010017
摘    要:目的:评价奥硝唑在治疗厌氧菌感染性牙周疾患中的疗效及全身副反应。方法:采用双盲随机方法选择门诊100例牙周疾患者。其中受试组(奥硝唑)50例和对照组(甲硝唑)50例进行临床治疗对比。观察疗效并记录其副反应进行比较。结果:二者疗效无显著性差异。奥硝唑副反应小,而甲硝唑副反应大,尤其是对胃肠道的刺激性更为显著。结论:奥硝唑对治疗牙周炎效果显著且副作用小于甲硝唑。

关 键 词:奥硝唑  甲硝唑  牙周炎  厌氧菌
文章编号:1004-0951(2006)07-0591-02
收稿时间:2006-03-23
修稿时间:2006-03-23

Efficacy and Side Effect of Ornidazole and Metronidazole in Treatment of Periodontitis
ZHANG Li-ying,LIU Xiao-long,GAO Yong-zhen,CHEN Li-chun. Efficacy and Side Effect of Ornidazole and Metronidazole in Treatment of Periodontitis[J]. Inner Mongolia Medical Journal, 2006, 38(7): 591-592
Authors:ZHANG Li-ying  LIU Xiao-long  GAO Yong-zhen  CHEN Li-chun
Affiliation:Department of Stomatology, Inner Mongolia Hospital, Huhhot 010017 China
Abstract:Objective:To evaluate the curative effect and systematic side effect of ornidazole in treating infective periodontitis induced by anaerobe.Methods:100 patients of periodontitis in out-patient clinic were randomly selected and divided into two groups:treatment group with ornidazole and control group with metronidazole.The curative effect and its side effect were observed and compared.Results:There was no significant difference in curative effect between treatment group and control group.The side effect of metronidazole was more severe than that of or nidazole,especially irritation of gastrointestinal tract.Conclusions:Compared with metronidazole,ornidzole is more effective and safe medicine for periodontitis.
Keywords:Oronidazole  Metronidazole  Periodontitis  Anaerobe
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