三维增强磁共振肺动脉血管造影诊断急性肺栓塞的实验研究

目的 探讨钆喷替酸葡甲胺（Ｇｄ－ＤＴＰＡ）三维增强共振肺动脉血管造影成像（３ＤＣＥＭＲＰＡ）在急性肺栓塞（ｐｕｌｍｏｎａｒｙ ｅｍｂｏｌｉｓｍ，ＰＥ）中的诊断价值。方法 对１７只自体血栓引发的犬急性肺栓塞模型，利用３Ｄ快速扰相梯度回波序列（ＦＳＰＧＲ）行３Ｄ ＣＥＭＲＰＡ检查和Ｘ线肺动脉血管造影（Ｘ－ｒａｙ ｐｕｌｍｏｎａｒｙ ａｎｇｉｏｇｒａｐｈｙ，ＸＰＡ）检查，并与病理解剖对照。

Diagnosisof acute pulmonary embolism with contrast-enhancedMR angiography: an experimental study

Objective To assess the diagnostic value of three dimensional contrast enhanced magnetic resonance pulmonary angiography (3D CEMRPA) with dadolinium DTPA in acute pulmonary embolism (PE) Methods Seventeen dogs with acute pulmonary embolism induced by autologous blood clots were examined with 3D CEMRPA using a fast spoiled gradient echo technique and with X ray pulmonary angiography (XPA) The findings were compared with pathological dissection Results The 3D CEMRPA signs of acute PE were: total vessel occlusion(30/41), pulmonary perfusion defect (23/41), partial filling defect (3/41) and central filling defect (1/41) in the pulmonary artery The sensitivity of 3D CEMRPA was 82 9%, specificity 98 2%, whereas the sensitivity and specificity of XPA was 75 6%, 97 9%, respectively Conclusion 3D CEMRPA for the detection of acute PE demonstrates high sensitivity and specificity, but the technique needs to be confirmed by further clinical trials