甘草甜素和多索茶碱联合治疗儿童支气管哮喘的疗效观察

目的观察甘草甜素联合多索茶碱治疗儿童支气管哮喘的临床疗效及安仝性。方法对符合诊断标准的75例支气管哮喘患儿分为忖草甜素联合多索茶碱组25例，地搴米松联合氨茶碱组25例，对照组25例。观察3组疗效和不良反应。结果甘草甜素联合多索荥碱组临床治疗效果最好，未发现不良反应。地塞米松联合氨茶碱组临床治疗效果好，有部分患儿出现体内脂肪重新分布的情况。对照组疗效差．差异有显著性（P〈0．05）。结论仲草甜素联合多索茶碱对支气管哮喘患儿的冶疗疗效妤，不良反应少。同时甘草甜素具有激素所没有的免疫调节功能。

Therapeutic effect of Glycyrrhizin combined with Doxofylline in treatment of childhood bronchial astluna

Objective To analyze the therapeutic effect and safly of glycyrrhizin and doxofylline in the treatment of childhood bronchial asthma. Methods According to the diagnostic criteria, 75 children who suffered from childhood bronchial asthma were divided to 3 groups randomly. Group A： glycyrrhizin and doxofylline＇, group B： dexamethasone and aminophylline, group C ： control group, 25 cases each. Observe the therapeutic effect and side effect respectively. Results Group A demonstrated to be the best, without side effects. Group B resulted in satisfhctory therapeutic effect, accompanying with a partially relocation of fat. Group C showed the worst therapeutic effect, with obvious difference （ P 〈 0.05 ）. Conclusion Treatment of childhood bronchial asthma with glycyrrbizin and doxofylline proved to be good effect, with less side effects. Besides, gtycyrrhizin possesses immune regulation effect, while corticotrophin doesn＇t.