复方南星止痛膏治疗寒湿痹阻型膝骨性关节炎中医证侯积分研究

目的评价复方南星止痛膏治疗膝骨性关节炎（寒湿痹阻证）的中医证侯积分影响。方法随机将418例患者分为治疗组316例（复方南星止痛膏组）和对照组102例（骨痛贴膏），疗程2w，观察治疗后两组患者的临床疗效和中医证侯疗效，及治疗前后膝骨性关节炎中医证侯积分的变化。结果①与治疗前相比，两组患者的膝骨性关节炎临床疗效和中医证侯疗效都较明显（P〈0．05），膝骨性关节炎中医证侯积分明显下降（P〈0．01）；②治疗后两组间比较，膝骨性关节炎临床疗效和中医证侯疗效差异有统计学意义（P〈0．05），中医证侯积分亦差异有统计学意义（P〈0．05），余差异无统计学意义（P〉0．05）。结论复方南星止痛膏治疗膝骨性关节炎（寒湿痹阻证）疗效确切，安全，无毒副作用，不良反应少，值得临床推广使用。

Compound treatment of prolonged cold-damp obstruction type of knee osteoarthritis study of TCM points

Objective To evaluate the analgesic compound Southern Star Ointment treatment of knee arthritis （alpine Bizu certificate） the impact of TCM points. Methods 418 cases of patients were randomly divided into treatment group 316 cases （compound Southern Star Rub group） and the control group 102 cases （pain Plaster）, treatment 2 weeks after treatment both groups of patients with the clinical efficacy and efficacy of TCM, and treatment of knee osteoarthritis before and after the TCM sub-changes. Results （!）compared with those before treatment, two groups of patients with knee osteoarthritis clinical efficacy and efficacy of TCM are more obvious （P〈0.05）, traditional Chinese medicine symptoms of knee osteoarthritis points decreased significantly （P〈0.01） ;（2）between the two groups after treatment compared to knee osteoarthritis clinical efficacy and efficacy of TCM were significantly different （P〈0.05）, TCM is also a significant difference in points （P〈0.05）, I was no significant difference （P〉0.05）. Conclusion The compound Southern Star Rub knee osteoarthritis （alpine Bizu card） the exact effective, safe, non-toxic side effects, adverse reactions less worthy of clinical use.