脑血栓形成复发的危险因素研究

目的：探讨脑血栓形成复发的危险因素。方法：收集首发441例脑血栓形成患者的临床资料，采用前瞻性队列研究，随访1年，记录终点事件。结果：脑血栓形成1年复发率为t3．8％；年龄（P=0．002，OR=1．044，95％CI=1．015～1．073）、高血压病史（P=0．040，OR=I．944，95％CI=1．032～3．663）、纤维蛋白原（P=0．000，OR=I．932，95％CI=1．386～2．666）为影响脑血栓形成复发的因素。结论：高龄、高血压病史及纤维蛋白原升高是脑血栓形成复发的重要危险因素。

Studies of Risk Factors of Patients with Cerebral Infarction

Aim： Cerebral Infarction is one of important diseases with high morbidity rate, high mortality rate, high disable rate and high recurrent rate. The purpose of this study was to identify the risk factors of recurrent cerebral infarction. Methods： The clinical data of the first-event cerebral infarction patients were gathered. 441 cases were followed up in a year since the first event. The recurrent ischernic strokes were memorized. For the statistical analysis, Logistic regression models were used to calculate which factors contributed to recurrence. Results： The recurrent rate was 13.8%. The main stroke recurrence factors with statistical significance include： age（P=0.002, OR=1.044, 95%CI=1.015-1.073）, hypertension history （P=0.040, OR=1.944, 95%CI=1.032-3.663）, FIB（P=0.000, OR=1.932, 95%CI=1.386-2.666）. Conclusion： The rate of recurrent cerebral infarction is 13.8% within a year. Old age, hypertension history and fibrinogen increasing are the risk factors of recurrent cerebral infarction.