| 人衰老成纤维细胞c-myc原癌基因的损伤修复 |
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| 引用本文： | 毛泽斌,张宗玉,童坦君.人衰老成纤维细胞c-myc原癌基因的损伤修复[J].北京大学学报(医学版),1997(1). |
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| 作者姓名： | 毛泽斌 张宗玉 童坦君 |
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| 作者单位： | 北京医科大学生物化学与分子生物学系!100083 |
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| 摘 要： | 目的：观察人衰老成纤维细胞特异因基c-myc的损伤修复。方法；采用Southern杂交法。结果：衰老细胞能有效地修复c－myc基因。结论：衰老细胞能有效地修复对细胞存亡至关重要的基因。
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| 关 键 词： | 成纤维细胞 原癌基因c－myc 细胞衰老 |
DAMAGE AND REPAIR OF THE c-myc PROTO-ONCOGENE IN SENESCENT HUMAN DIPLOID FIBROBLAST CELLS |
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| MAO Zebin, ZHANG Zongyu, TONG TanJun.DAMAGE AND REPAIR OF THE c-myc PROTO-ONCOGENE IN SENESCENT HUMAN DIPLOID FIBROBLAST CELLS[J].Journal of Peking University:Health Sciences,1997(1). |
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| Authors: | MAO Zebin ZHANG Zongyu TONG TanJun |
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| Abstract: | To investigate the ability of proto-oncogene c-myc repair in senescent humandiploid fibroblast cells. Methods: Southern blot. Results: Although genomic DNA repair ability insenescence was low compared with young cells, The ability of proto-oncogene c-myc repair was similarin both cells, Conclusion: An essential and active gene may be effectively repaired even in senescentcells. |
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| Keywords: | Fibroblasts Proto-oncogene c-myc Cell aging |
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