颌骨骨质疏松的影响因素

目的:随着人类寿命的延长,越来越多的人们开始关注健康。本文总结了有关颌骨骨质疏松的研究成果,探讨阻止或延缓颌骨骨质疏松发生的原因,改善人们的生活质量。资料来源:应用计算机检索清华同方数据库1991-01/2005-05关于颌骨骨质疏松的相关文献,检索词为“骨质疏松,上颌骨,下颌骨”,限定语言类型为中文。同时计算机检索Medline1975-01/2005-05的相关文献,检索词为“osteoporosis,mandiblebone,alveolarbone”,并限定语言种类为英文。资料选择:从资料中选取包括颌骨骨质疏松研究数据的文献。纳入标准:所有关于颌骨骨质疏松研究的随机对照试验、药物负荷试验和药物疗效临床试验;研究群体包括人类和动物。排除标准:综述类文献,没有对照组文献。资料提炼:共收集到182篇关于颌骨骨质疏松的文献,36篇符合纳入标准。排除的146篇是重复的同一药物疗效研究。资料综合:符合纳入标准的36篇文献,包括了5321例患者和152例动物,从年龄、性别、激素、咬合力、体育锻炼以及生活习惯等方面分别对影响颌骨骨质疏松的因素进行研究,其中6篇是动物切除卵巢后进行的干预试验。结论:颌骨骨质疏松是全身骨矿丢失的一部分,受年龄、性别、激素、咬合力、体育锻炼以及生活习惯等因素的影响。

Influencing factors of mandible osteoporosis

OBJECTIVE: With the prolongation of life span, more and more people care their health. In this paper we summarized the studies about correlative factors of mandible osteoporosis so as to investigate the cause of osteoporosis and how to inhibit or postpone the occurrence of mandible osteoporosis and improve people's quality of life.DATA SOURCES: We searched Qsinghua Tongfang Database for papers about mandible osteoporosis published between January 1991 and May 2005 with the key words of "osteoporosis, mandible bone, alveolar bone"in Chinese. Meanwhile, related English literatures were also searched in Medline between January 1975 and May 2005 with the same key words.STUDY SELECTION: The literatures included all the related papers of correlative factors of mandible osteoporosis. Inclusive criteria were: the study types were randomized controlled trials, drug stress test and clinical drug effect test; the samples were both human and animals. Exclusive criteria: Reviews and literatures without controls were excluded.DATA EXTRACTION: Totally 182 literatures related to the correlative factors of mandible osteoporosis were collected, and 36 were accorded with the inclusive criteria. The excluded were 146 papers of repeated drug effect study.DATA SYNTHESIS: A total of 36 papers including 5 321 human and 152 animals analyzed the data of correlative factors of mandible osteoporosis in age, sex, hormones, biting force, physical training and living habit,etc., respectively, which included 6 interfere-test papers of ovariactomized rats.CONCLUSION: It is concluded that mandible osteoporosis can result in a part of bone mine loss, which is related to age, sex, hormones, biting force,physical exercise and living habits, and so on.