丙泊酚复合瑞芬太尼在ERCP诊疗中的应用效果观察

目的观察丙泊酚复合瑞芬太尼在逆行胰胆管造影检查取石术中应用的麻醉效果．方法80例内镜逆行胰胆管造影（ERCP）检查取石患者，随机分为两组，单纯丙泊酚麻醉组（P组）；丙泊酚复合瑞芬太尼麻醉组（PR组），观察记录不同时点HR、MAP、RR、SpO2，镇静评分、手术时间、苏醒时间、丙泊酚、瑞芬太尼总用量、不良反应发生率及患者满意度．结果所有病例均能顺利完成操作，诱导入睡后P组MAP、RR下降（P〈0．05），PR组苏醒时间、丙泊酚总用量、不良反应发生率均少于P组（P〈0．05），镇静评分优于P组（P〈0．05）、手术时间及患者满意度无差异性．结论丙泊酚复合瑞芬太尼适用于ERCP诊疗中，是一种更为安全有效的麻醉方法．

Application of Propofol Combined with Remifentanil in Endoscopic Retrograde Cholangio Pancreatography

Objective To investigate the application of propofol combined with remifentanil for aneasthesia in endoscopic retrograde eholangio pancreatography （ERCP）. Method Eighty patients for elective ERCP were randomly divided into 2 groups with 40 patients each, propofol group （group P） and propofol combined with remifentanil group （group PR）. HR, MAP, RR, SpO2, sedative score, dosage of propofol and remifentanil, adverse effects were recorded. Results The patients of all groups were quiet and stable.After induction, MAP, RR in group P were lower than those in group PR （P 〈 0.05）. The dosage of propofol, the rate of adverse effects and sedative score in group PR were lower than those in group P.The operating time of the groups was not significantly different （P 〉 0.05 ）. Conclusion It is safe and available for propofol combined with remifentanil in ERCP.