| 淋巴结外弥漫大B细胞淋巴瘤分子分型的病理学研究 |
| |
| 引用本文： | 彭晚娇,姚丽青,郑智勇. 淋巴结外弥漫大B细胞淋巴瘤分子分型的病理学研究[J]. 实用癌症杂志, 2010, 25(1): 59-61 |
| |
| 作者姓名： | 彭晚娇 姚丽青 郑智勇 |
| |
| 作者单位： | 1. 福建省级机关医院病理科,350003
2. 南京军区福州总医院病理科,350025 |
| |
| 摘 要： | 目的探讨结外弥漫大B细胞淋巴瘤（diffuse large B-celll ymphoma，DLBCL）分子分型及免疫组化特点，为临床治疗和预后评估提供帮助。方法采用免疫组化法，标记88例结外原发性弥漫大B细胞淋巴瘤中CD10、bcl-6、MUM1、ki-67的表达并进行分子分型。结果88例结外DLBCL中生发中心B细胞样（GCB）36例，非生发中心B细胞样（non—GCB）52例，GCB组中ki-67的阳性表达率大于75．0％有17例，占47．2％（17／36），non—GCB组中ki-67的阳性表达率大于75．0％有37例，占71．2％（37／52）。结论结外DLBCL以non—GCB多见。
|
| 关 键 词： | 结外淋巴瘤 弥漫大B细胞淋巴瘤 免疫组化 分子分型 |
Lymph Nodes Outside the Diffuse Large B-cell Lymphoma Molecular Pathology-based Research |
| |
| PENG Wan-jiao,YAO Li-qing,ZHENG Zhi-yong. Lymph Nodes Outside the Diffuse Large B-cell Lymphoma Molecular Pathology-based Research[J]. The Practical Journal of Cancer, 2010, 25(1): 59-61 |
| |
| Authors: | PENG Wan-jiao YAO Li-qing ZHENG Zhi-yong |
| |
| Affiliation: | PENG Wan-jiao,YAO Li-qing,ZHENG Zhi-yong. Hospital-level Authorities in Fujian Province Pathology,Fuzhou,350003 |
| |
| Abstract: | Objective to discuss molecular typing and immunohistochemical properties of extranodal diffuse large B-cell lymphoma (DLBCL) for helping clinical treatment and prognosis evaluation.Methods expressions of CD10,bcl-6,MUM1 and ki-67 in 88 cases of extranodal primary diffuse large B-cell lymphoma were labeled by immunohistochemical method.Results 36 germinal center B-cell like (GCB) cases and 52 nongerminal center B-cell like (non-GBC) cases occurred among 88 cases of extranodal DLBCL.In GBC group,there were 17... |
| |
| Keywords: | Extranodal lymphoma Diffuse large B-cell lymphoma (DLBCL) Immunohistochemistry Molecular typing |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
