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HIV-1 Nucleocapsid Protein Binds Double-Stranded DNA in Multiple Modes to Regulate Compaction and Capsid Uncoating
Authors:Helena Gien  Michael Morse  Micah J. McCauley  Jonathan P. Kitzrow  Karin Musier-Forsyth  Robert J. Gorelick  Ioulia Rouzina  Mark C. Williams
Affiliation:1.Department of Physics, Northeastern University, Boston, MA 02115, USA; (H.G.); (M.M.); (M.J.M.);2.Department of Chemistry and Biochemistry, Center for Retroviral Research and Center for RNA Biology, Ohio State University, Columbus, OH 43210, USA; (J.P.K.); (K.M.-F.); (I.R.);3.AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA;
Abstract:
Keywords:DNA condensation   optical tweezers   atomic force microscopy   capsid uncoating   HIV-1 nucleocapsid protein
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