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Low-Risk Surgical Aortic Valve Replacement in the Era of Transcatheter Aortic Valve Implantation
Authors:Milos M. Jovanovic  Slobodan V. Micovic  Miodrag S. Peric  Igor S. Zivkovic  Stasa D. Krasic  Ognjen S. Milicevic  Stefan P. Stankovic  Petar M. Vukovic
Affiliation:1. Department of Cardiac Surgery, Dedinje Cardiovascular Institute, Belgrade, Serbia ; 2. Department of Cardiology, Mother and Child Health Care Institute of Serbia, Belgrade, Serbia ; 3. Department of Medical Statistics and Informatics, School of Medicine, University of Belgrade, Belgrade, Serbia
Abstract:Open surgical aortic valve replacement (SAVR) is a viable alternative to transcatheter implantation in low-risk patients. In this light, we evaluated the safety and effectiveness of SAVR performed through conventional and less invasive surgical approaches in a high-volume center.We retrospectively reviewed the records of 395 consecutive patients who underwent open SAVR from January 2019 through December 2019 in our center. We evaluated and compared the operative results and postoperative major adverse outcomes of 3 surgical approaches: full median sternotomy (n=267), upper ministernotomy (ministernotomy) (n=106), and right anterior thoracotomy (minithoracotomy) (n=22).Overall, the 30-day all-cause mortality rate was 0.8% (3 patients). Stroke occurred in 8 patients (2%), disabling stroke in 4 patients (1%), myocardial infarction in 1 (0.2%), and surgical site infection in 13 (3.2%). There was no difference in 30-day mortality rate or incidence of postoperative major adverse events among the 3 surgical groups. Stroke and surgical site infection occurred more frequently, but not significantly so, in the full-sternotomy group. The mean hospital stay was longer after full sternotomy (9.1 ± 5.5 d) than after ministernotomy (7.5 ± 2.9 d) or minithoracotomy (7.4 ± 1.9 d) (P=0.012).Our findings suggest that open SAVR performed in a high-volume center is associated with a low early mortality rate and that less invasive approaches result in faster postoperative recovery and shorter hospital stays.
Keywords:Aortic valve stenosis/surgery   heart valve prosthesis implantation   minimally invasive surgical procedures   sternotomy   sutureless surgical procedures   thoracotomy   transcatheter aortic valve replacement   treatment outcome
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