| 四种辅助治疗方案联合手术对中晚期食管癌疗效的对比研究 |
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| 引用本文： | 左传田,茅乃权,刘德森,黄鼎铭,潘泓,谢彤,黄耀元,潘琪,杨立. 四种辅助治疗方案联合手术对中晚期食管癌疗效的对比研究[J]. 肿瘤学杂志, 2011, 17(7): 518-520 |
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| 作者姓名： | 左传田 茅乃权 刘德森 黄鼎铭 潘泓 谢彤 黄耀元 潘琪 杨立 |
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| 作者单位： | 广西医科大学附属肿瘤医院,广西 南宁,530021 |
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| 基金项目： | 广西科学基金项目（桂科回0342024） |
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| 摘 要： | [目的]分析辅助治疗对中晚期食管癌的临床价值。[方法]230例中晚期食管癌（T2-4NXMO）患者,按照治疗方法分成4组,NRT组予术前放疗,NCRT组予术前放化疗,PRT组予术后放疗,PCRT组予术后放化疗,分析4组复发率、5年生存率。[结果]NRT、NCRT、PRT、PCRT组1年局部复发率分别为72.8%、30.7%、80.1%、35.6%,差异有显著性（χ2=4.159,P=0.000）;5年生存率分别为8.82%、33.33%、14.28%和19.18%,差异有显著性（χ2=13.812,P=0.003）。[结论]术前放化疗治疗中晚期食管癌可降低局部复发率,并提高远期生存率。
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| 关 键 词： | 食管肿瘤 术前放疗 术前放化疗 生存率 |
A Comparison of Surgery with Four Different Adjuvant Therapies in the Treatment for Advanced Esophageal Cancer |
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| ZUO Chuan-tian,MAO Nai-quan,LIU De-sen,et al.. A Comparison of Surgery with Four Different Adjuvant Therapies in the Treatment for Advanced Esophageal Cancer[J]. Journal of Chinese Oncology, 2011, 17(7): 518-520 |
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| Authors: | ZUO Chuan-tian MAO Nai-quan LIU De-sen et al. |
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| Affiliation: | ZUO Chuan-tian,MAO Nai-quan,LIU De-sen,et al. (Tumor Hospital,Guangxi Medical University,Nanning 530021,China) |
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| Abstract: | [Purpose] To investigate the clinical efficacy of surgery with four adjuvant therapies in the treatment for advanced esophageal cancer(AEC). [Methods] A total of 230 cases wtih AEC T2~4NXM0 were divided into 4 groups: radiotherapy followed by surgery(NRT-group), chemoradiotherapy followed by surgery (NCRT-group), radiotherapy after surgery(PRT-group) and chemoradiotherapy after surgery(PCRT-group). Recurrence rate and 5-year survival in 4 groups were analyzed. [Results] The recurrence rate was 72.8%,30.7%,8... |
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| Keywords: | esophageal neopalsms neoadjuvant radiotherapy neoadjuvant chemoradiotherapy survival |
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