硫酸镁用于肠镜前肠道准备的临床效果研究

目的 探讨进行结肠镜检查的患者全肠道准备的最佳方法,以提高肠道检查及治疗的成功率,减少不适反应的发生.方法 选取准备进行结肠镜检查的患者120例,随机分为A、B、C 3组各40例,A组患者于检查当日晨口服硫酸镁100ml,服药后分次饮水6000ml;B组患者于检查前晚口服硫酸镁50ml并饮水2000ml,当日晨起口服硫酸镁50ml并分次饮水4000ml;C组患者于检查当日晨口服50%硫酸镁100ml,同时急饮4000～5000ml水.同时指导A、B2组患者进行适量活动及健康宣教,比较3组患者肠道准备的效果.结果 B组肠道清洁度优于其他2组(P<0.05),B组患者的不适反应较少,与C组相比差异有统计学意义(P<0.01).结论 早晚口服硫酸镁进行肠道准备可使肠道清洁度高,有利于观察病变部位,不适反应少,检查结果满意,患者容易接受.

Clinical effect study of magensium sulfate on the intestine preparation before colonoscopy examination

Objective We discussed the optimal method for intestinal preparation before colonoscopy examination in order to increase the success rate of intestinal examination and reduce the incidence of adverse effect. Methods We divided 120 patients who were to undergo colonoscopy examination into group A, B and C with 40 cases in each group. Group A received oral magensium sulfate 100ml and 6000ml water after that on the morning of the examination. Group B received oral magensium sulfate 50ml and 2000ml in the evening before the examination, oral magensium sulfate 50ml and 400ml water on the morning of the examination. Group C was given oral magensium sulfate 100ml and 4000～5000 water at the same time. Group A and B took part in appropriate activity and were given health education. The effect of intestinal preparation was compared between the three groups. Results The cleaning degree of group B was better than those of the other two groups (P<0.05). The adverse effect of group B was less than that of group C (P<0.01). Conclusions Oral intake of magensium sulfate in the evening before and on the morning of the examination for intestinal preparation could increase the cleaning degree of intestine, facilitate the observation of disease part and lessen adverse effect. It gave satisfying examination results and made patients satisfied.