Sports drug testing and the athletes' exposome |
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| Authors: | Mario Thevis Tiia Kuuranne Matthew Fedoruk Hans Geyer |
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| Institution: | 1. Center for Preventive Doping Research - Institute of Biochemistry, German Sport University Cologne, Cologne, Germany;2. Swiss Laboratory for Doping Analyses, University Center of Legal Medicine, Genève and Lausanne, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Epalinges, Switzerland;3. United States Anti-Doping Agency (USADA), Colorado Springs, Colorado, USA;4. Center for Preventive Doping Research - Institute of Biochemistry, German Sport University Cologne, Cologne, Germany
European Monitoring Center for Emerging Doping Agents, Cologne, Germany |
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| Abstract: | Similar to the general population, elite athletes are exposed to a complex set of environmental factors including chemicals and radiation and also biological and physical stressors, which constitute an exposome that is, unlike for the general population, subjected to specific scrutiny for athletes due to applicable antidoping regulations and associated (frequent) routine doping controls. Hence, investigations into the athlete's exposome and how to distinguish between deliberate drug use and different contamination scenarios has become a central topic of antidoping research, as a delicate balance is to be managed between the vital and continually evolving developments of sensitive analytical techniques on the one hand, and the risk of the athletes' exposome potentially causing adverse analytical findings on the other. |
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| Keywords: | adverse analytical finding contamination doping drug exposure sport |
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