颅脑损伤后中枢性低钠血症的诊治

目的:分析颅脑损伤并发中枢性低钠血症的临床特点、诊断和治疗。方法:回顾分析近10年收治的25例颅脑损伤后中枢性低钠血症的临床资料。结果:本组抗利尿激素分泌异常综合征11例,治愈8例,死亡3例;脑耗盐综合征14例,治愈12例,死亡2例。结论:抗利尿激素分泌异常综合征和脑耗盐综合征的发病机制、临床表现和治疗都不相同,早期诊断和治疗可以降低病人的死亡率。

The Diagnosis and Treatment of Central Hyponatremiaafter Craniocerebral Injury

Objective: To analyze the clinical characteristic and its diagnosis and treatment of central hyponatremia after craniocerebral injury. Methods: The clinical manifestation and material of 25 patients with central hyponatremia after craniocerebral injury were investigated. Results: Syndrome of inappropriate antidiuretic hormone was found in 11 cases,with which 8 cases were cured and 3 cases died. Cerebral salt wasting syndrome were found in 14 cases,with which 12 cases were cured and 2 cases died. Conclusions: The pathogenesis and management of syndrome of inappropriate antidiuretic hormone(SIADH) is different from that of cerebral salt wasting syndrome(CSWS), and early diagnosis and therapy could reduce its morbidity and mortality.