| 酸枣仁颗粒中酸枣仁皂苷A和酸枣仁皂苷B的含量测定 |
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| 引用本文： | 周庆武,李玲玲,纪标,徐垣义.酸枣仁颗粒中酸枣仁皂苷A和酸枣仁皂苷B的含量测定[J].中国药业,2007,16(17):11-12. |
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| 作者姓名： | 周庆武 李玲玲 纪标 徐垣义 |
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| 作者单位： | 上海海尼药业有限公司,上海,201318 |
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| 摘 要： | 目的建立酸枣仁颗粒中酸枣仁皂苷A和酸枣仁皂苷B的含量测定方法。方法采用反相高效液相色谱法，分析柱为Hypersil C18柱，以乙腈和水为流动相的二元梯度洗脱方法，检测波长为201nm，流速为1 mL／min。结果酸枣仁皂苷A进样量在0．50-1．98μg与峰面积呈良好的线性关系（r=0.9998，n=5），平均回收率为99．41％；酸枣仁皂苷B进样量在0．66～2．09μg与峰面积呈良好的线性关系（r=0．9998，n=5），平均回收率为99．34％。结论该法简便、快速、重现性好，适用于酸枣仁颗粒中酸枣仁皂苷A、酸枣仁皂苷B的定量分析。
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| 关 键 词： | 反相高效液相色谱法 酸枣仁皂苷A 酸枣仁皂苷B 酸枣仁颗粒 含量测定 |
| 文章编号： | 1006-4931（2007）17-0011-02 |
| 修稿时间： | 2007-05-25 |
Determination of Jujubaside A and Jujubaside B in Ziziphus Jujuba Mill Granules |
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| Zhou Qingwu,Li Lingling,Ji Biao,Xu Yuanyi.Determination of Jujubaside A and Jujubaside B in Ziziphus Jujuba Mill Granules[J].China Pharmaceuticals,2007,16(17):11-12. |
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| Authors: | Zhou Qingwu Li Lingling Ji Biao Xu Yuanyi |
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| Institution: | Shanghai Haini Pharmaceutical Co., Ltd., Shanghai, China 201318 |
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| Abstract: | Objective To develop a method for the determination of jujubaside A and jujubaside B in ziziphus jujuba mill granules （ZJMG）. Methods A RP- HPLC method was set up, using Hypersil 18 column. The mobile phase consisted of acetonitrile and water, and a gradient elution program was applied. The DAD detector was set at 201 nm. Results The calibration curve of jujubaside A was linear in the range of 0.50-1.98 μg. The average recovery rate was 99.41%.The calibration curve of jujubaside B was linear in the range of 0.66-2.09 μg. The average recovery rate was 99.34%. Conclusion The method is appropriate for the determination of jujubaside A and jujubaside B. |
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| Keywords: | RP-HPLC jujubaside A jujubaside B ziziphus jujuba mill granules(ZJMG) content determination |
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