甲状腺机能亢进的动脉栓塞治疗

目的探讨栓塞甲状腺动脉治疗甲状腺机能亢进的方法并观察疗效。方法使用聚乙烯醇颗粒栓塞12例甲状腺机能亢进病人的30支甲状腺动脉。结果12例病人栓塞后1个月内血清三碘甲状腺氨酸中位值自7．8nmol／L（4．1～35．0nmol／L）降至3．8nmol／L（0．95～8．9nmol／L），甲状腺素中位值自182．6nmol／L（75．4～685．6nmol／L）降至135．5nmol／L（23．8～225．7nmol／L），（P〈0．01）。临床症状缓解或消失。随访超过6个月的7例在停用或间接使用抗甲状腺药物的情况下可有效控制症状。未见发生甲状腺功能低下或甲状旁腺功能异常。结论作为手术和1311治疗的替代疗法，甲状腺动脉栓塞是甲状腺机能亢进综合治疗中可供选择的有效手段。其长期疗效有待进一步观察。

Thyroid Artery Embolization Therapy of Hyperthyroidism

Objective To evaluate the method and result of thyroid artery embolization as a new therapy for hyperthyroidism. Methods Twelve patients with hyperthyroidism underwent selective thyroid artery embolization with PVA microspheres. Total 30 thyoid arteries were embolized with PVA . Results Serum level of thyroid hormones dropped significantly median T3 from 7.8nmol/L(4.1~35.0 nmol/L)to 3.8 nmol/L(0.95~8.9 nmol/L),median T4 from 182.6 nmol/L(75.4~685.6 nmol/L) to 135.5 nmol/L(23.8~225.7 nmol/L),P<0.01.The symptoms of hyperthyroidism were controlled. The symptoms of seven patients were effectively controled for more than 6 months through low dose antithyroid medication. No hypothyroidism and hypoparathyroidism were observed after the interventional procedure. Conclusion Thyroid artery embolization is an effective alternative for surgical and I131 treatment of hyperthyroidism.A long term follow-up study is still needed .