| PET报告基因显像 |
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| 引用本文： | 陈虞梅,黄钢.PET报告基因显像[J].国际放射医学核医学杂志,2006,30(3):139-141. |
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| 作者姓名： | 陈虞梅 黄钢 |
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| 作者单位： | 1. 200127 上海, 上海交通大学医学院附属仁济医院核医学科; |
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| 基金项目： | 上海市科委重点基金项目(02DJ14037)，上海市百人计划第三轮重点资助项目(97BR012) |
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| 摘 要： | 运用正电子发射体层显像(PET)及相关的PET报告基因及报告探针的活体显像技术可提供关于基因治疗定量及定性的信息,并可提供其他技术不能获得的参数,这对更好地理解基因治疗的过程及人类基因治疗的未来发展及临床应用很有意义。
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| 关 键 词： | 体层摄影术 发射型计算机 基因 报告 |
| 文章编号： | 1673-4114(2006)03-0139-03 |
| 收稿时间： | 2005-08-30 |
| 修稿时间： | 2005年8月30日 |
Investigation progress of PET reporter gene imaging |
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| CHEN Yu-mei,HUANG Gang.Investigation progress of PET reporter gene imaging[J].International Journal of Radiation Medicine and Nuclear Medicine,2006,30(3):139-141. |
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| Authors: | CHEN Yu-mei HUANG Gang |
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| Institution: | 1. Department of Nuclear Medicine, Renji Hospital, Shanghai Jiaotong University, Shanghai, 200127, China; |
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| Abstract: | Molecular imaging for gene therapy and gene expression has been more and more attractive, while the use of gene therapy has been widely investigated and intense research have allowed it to the clinical setting in the last two-decade years. In vivo imaging with positron emission tomography (PET) by combination of appropriate PET reporter gene and PET reporter probe could provide qualitative and quantitative information for gene therapy. PET imaging could also obtain some valuable parameters not available by other techniques. This technology is useful to understand the process and development of gene therapy and how to apply it into clinical practice in the future. |
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| Keywords: | Tomography emission-computed Gene reporter |
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