200例子宫平滑肌肿瘤临床与病理分析

目的探讨子宫平滑肌肿瘤临床病理特征。方法对200例子宫平滑肌肿瘤的临床病理资料进行回顾性分析。结果子宫平滑肌肿瘤发生的最小年龄24岁,最大年龄61岁,平均年龄43.3岁,高发年龄41～50岁。子宫平滑肌肿瘤可同时与子宫内膜增生、腺肌病、卵巢各种囊肿及多种良恶性病变并存。在200例子宫平滑肌肿瘤中,普通平滑肌瘤196例,恶性潜能未定的平滑肌肿瘤3例,平滑肌肉瘤1例。结论子宫平滑肌瘤是常见肿瘤,可同时与子宫、卵巢各种良恶性病变同时存在。在子宫平滑肌良恶性肿瘤的鉴别诊断中,核分裂数是诊断良恶性子宫平滑肌肿瘤的重要指标,但不是唯一指标,应结合细胞异型性及周围有无浸润等临床资料作出诊断。

Analysis the Clinical Pathology of 200 Cases Uterine Smooth Muscle Tumors

Objective: To investigate the clinicoal pathology of uterine smooth muscle tumors. Method: Clinical and pathological data of 200 cases of uterine smooth muscle tumors were analyzed retrospectively. Result : The youngest who suffers from uterine leiomyoma is 24 years old ,the oldest is 61, the mean age is 43.3 .And the ones whose age is between 41 and 50 have the highest happening rate. Uterine smooth muscle may coexist with other diseases such as endometrial hyperplasia ,ademomyosis ,all kinds of cysts of ovary ,all kinds of benign or malignant tumours et al. Among 200 cases of the tumors ,there were 196 cases of usual leiomyoma ,3 smooth muscle tumor of uncertain malignant potential and 1 leiomyosarcoma. Conclusion : The uterine leiomyoma is easy to be found and may coexist with all kinds of disease of uterus and ovary . Nuclear mitotic activity is an important but not sole criterion in the diagnosis of benign or malignant uterine smooth muscle tumors;the combination of cellular atypia,margin infiltration,clinical data should also be taken into consideration.