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| 卵巢良性肿瘤组织和卵巢上皮癌组织基因表达差异的研究 | |
| 引用本文： | 朱根海,杨舒盈,王历,杨剑国,陈春英,金丽华,Frank Yelian.卵巢良性肿瘤组织和卵巢上皮癌组织基因表达差异的研究[J].中国优生与遗传杂志,2007,15(8):34-36. |
| 作者姓名： | 朱根海 杨舒盈 王历 杨剑国 陈春英 金丽华 Frank Yelian |
| 作者单位： | 1. 海南省人民医院妇科,海口,570311 2. 海南省人民医院研究中心,海口,570311 3. Department of Obstetrics and Gynecology,Wayne State University,Detroit,MI 48201,USA |
| 摘 要： | 目的 探讨卵巢上皮癌组织相关基因的差异表达.方法 采用含384条肿瘤相关基因的cDNA阵谱检测了卵巢上皮癌组织及卵巢良性肿瘤的基因谱,分析卵巢上皮癌组织相关基因的差异表达.结果 在384条候选基因中,与卵巢癌相关的差异表达基因36条,其中23条表达上调,13条表达下调.结论 cDNA阵谱技术是筛查卵巢癌相关基因的有效方法. |
| 关 键 词： | 卵巢肿瘤 cDNA阵谱 基因表达谱 |
| 文章编号： | 1006-9534（2007）08-0034-03 |
| 收稿时间： | 2007-02-12 |
| 修稿时间： | 2007年2月12日 |
Study of differential gene expression between benign ovarian tumor and epithelial ovarian cancer |
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| Frank Yelian.Study of differential gene expression between benign ovarian tumor and epithelial ovarian cancer[J].Chinese Journal of Birth Health & Heredity,2007,15(8):34-36. | |
| Authors: | Frank Yelian |
| Abstract: | Objective:To investigate the differential gene expression related to epithelial ovarian cancer.Methods:Gene expression profile and the differential gene expression between epithelial ovarian cancer and benign ovarian tumor were studied by cDNA array including 384 neoplastic-related genes.Results:Of 384 screened genes,36 differentially expressed genes related to epithelial ovarian cancer were found,23 genes were up-regulated and 13 were down-regulated.Conclusion:cDNA array is an effective methods in screening the candidate genes related to epithelial ovarian cancer. |
| Keywords: | Ovarian neoplasms cDNA array Gene expression profile |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |