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卵巢良性肿瘤组织和卵巢上皮癌组织基因表达差异的研究
引用本文:朱根海,杨舒盈,王历,杨剑国,陈春英,金丽华,Frank Yelian. 卵巢良性肿瘤组织和卵巢上皮癌组织基因表达差异的研究[J]. 中国优生与遗传杂志, 2007, 15(8): 34-36
作者姓名:朱根海  杨舒盈  王历  杨剑国  陈春英  金丽华  Frank Yelian
作者单位:1. 海南省人民医院妇科,海口,570311
2. 海南省人民医院研究中心,海口,570311
3. Department of Obstetrics and Gynecology,Wayne State University,Detroit,MI 48201,USA
摘    要:目的 探讨卵巢上皮癌组织相关基因的差异表达.方法 采用含384条肿瘤相关基因的cDNA阵谱检测了卵巢上皮癌组织及卵巢良性肿瘤的基因谱,分析卵巢上皮癌组织相关基因的差异表达.结果 在384条候选基因中,与卵巢癌相关的差异表达基因36条,其中23条表达上调,13条表达下调.结论 cDNA阵谱技术是筛查卵巢癌相关基因的有效方法.

关 键 词:卵巢肿瘤  cDNA阵谱  基因表达谱
文章编号:1006-9534(2007)08-0034-03
收稿时间:2007-02-12
修稿时间:2007-02-12

Study of differential gene expression between benign ovarian tumor and epithelial ovarian cancer
Frank Yelian. Study of differential gene expression between benign ovarian tumor and epithelial ovarian cancer[J]. Chinese Journal of Birth Health & Heredity, 2007, 15(8): 34-36
Authors:Frank Yelian
Abstract:Objective:To investigate the differential gene expression related to epithelial ovarian cancer.Methods:Gene expression profile and the differential gene expression between epithelial ovarian cancer and benign ovarian tumor were studied by cDNA array including 384 neoplastic-related genes.Results:Of 384 screened genes,36 differentially expressed genes related to epithelial ovarian cancer were found,23 genes were up-regulated and 13 were down-regulated.Conclusion:cDNA array is an effective methods in screening the candidate genes related to epithelial ovarian cancer.
Keywords:Ovarian neoplasms   cDNA array   Gene expression profile
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