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逍遥散加减方对慢性疲劳综合征(CFS)患者情绪状态及淋巴细胞凋亡的影响
引用本文:赵建明,刘雁峰,孔筠,董浩,张枢,陈家旭. 逍遥散加减方对慢性疲劳综合征(CFS)患者情绪状态及淋巴细胞凋亡的影响[J]. 陕西中医学院学报, 2006, 29(1): 51-53
作者姓名:赵建明  刘雁峰  孔筠  董浩  张枢  陈家旭
作者单位:1. 北京军区总医院中医科,北京,100026
2. 北京中医药大学东方医院,北京,100000
3. 中国康复中心,北京,100000
4. 北京中医药大学基础医学院,北京,100000
摘    要:目的研究CFS与患者情绪状态及外周血淋巴细胞凋亡的关系。方法采用治疗前后对照研究。结果CFS组治疗前情绪各状态明显高于健康对照组(P<0.05);逍遥散加减方治疗后CFS患者各种情绪及疲劳因子明显低于治疗前(P<0.01);CFS组治疗前淋巴细胞凋亡率明显高于健康对照组(P<0.01);逍遥散加减方治疗后CFS患者外周血淋巴细胞凋亡率明显低于治疗前(P<0.05);CFS组治疗前淋巴细胞中bcl-2表达明显高于健康对照组(P<0.01);逍遥散加减方治疗后CFS患者外周血淋巴细胞中bcl-2表达明显低于治疗前(P<0.05)。结论CFS的发病过程存在着细胞凋亡,而且中药有调节作用。

关 键 词:慢性疲劳综合征  情绪状态  淋巴细胞凋亡  逍遥散
文章编号:1002-168X(2006)01-0051-03
收稿时间:2005-11-09
修稿时间:2005-11-09

The Influence of Modified Xiaoyaosan on the Apoptosis of Lymphocytes and the Emotions of Chronic Fatigue Syndrome(CFS) patients
Zhao Jianming,Liu Yanfeng,Kong Jun,Dong Hao,Zhang Shu,Chen Jiaxu. The Influence of Modified Xiaoyaosan on the Apoptosis of Lymphocytes and the Emotions of Chronic Fatigue Syndrome(CFS) patients[J]. Journal of Shaanxi College of Traditional Chinese Medicine, 2006, 29(1): 51-53
Authors:Zhao Jianming  Liu Yanfeng  Kong Jun  Dong Hao  Zhang Shu  Chen Jiaxu
Affiliation:1. Chinese Medicine Department of Beijing General Military Hospital, Beijing 100026;2. DongFang Hospital of Beijing University of TCM, Beijing 100000;3. China Rehabilitation Center, Bijing 100000 ;4. Elementary College of Beijing University of TCM, Beijing 100000
Abstract:Objective To study the relationship between CFS and the patients's emotions and the apoptosis of lymphocytes.Methods To compare the differences after the treatment.Results The emotional condition of CFS group was worse(P<0.05) than the control group(P<0.01)before the treatment and better afterwards with the fatigue factor much lower(P<0.01).The apoptosis rate was much higher than the control group(P<0.05) before the treatment and much lower afterwards(P<0.01).So was the expression of bcl-2 of lymphocytes.Conclusion The apoptosis of cells exists in the process of CFS and TCM attaches a role of coordination.
Keywords:chronic fatigue syndrome  emotional state  lymph cell apoptosis  Xiaoyao Powder
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