急性百草枯中毒患者血清肌酸激酶MB与预后的关系

目的探讨急性百草枯中毒患者血清肌酸激酶MB（CK—MB）与预后的关系。方法急性百草枯中毒患者41例，以住院死亡为观察终点分为死亡组和存活组。采用酶法测定中毒后24小时内CK—MB的血清含量并进行统计分析。结果血清CK—MB增高的35例患者，病死率77．14％。死亡组CK—MB显著高于存活组。结论CK—MB在百草枯中毒24小时内明显增高的患者病情重，病死率高，预后差。早期动态监测CK—MB能客观评估病情程度及预后。

Correlation between serum level of creatine kinase of MB type and prognosis in acute paraquat-poisioned patients

Objective To study the correlation between serum level of creatine kinase of MB type(CK-MB) and prognosis in acute paxaquat-poisoned patients.Methods 41 patients with acute paraquat poisoning were divided into 2 groups:death group and survival group. The final clinical outcome was defined as either death or survival in hospita1.The serum level of CK-MB at 24 h after poisoning was detected by kinase method and analyzed by statistics.Results Mortality rate of 35 patients with elevated serum CK-MB was 77.14%(27 of 35). The serum level of CK-MB was significantly higher in death group than in survival group(P<0.05).Conclusion Acute paraquat-poisioned patients with elevated serum CK-MB often predict a severe status, poor prognosis,and high mortality rate.