超声联合胎儿纤维连接蛋白的早产预测

目的:通过100例早产病例分析,研究超声联合胎儿纤维连接蛋白(fFN)预测早产的意义。方法:于孕期利用宫颈超声检测,进行早产预测;孕中晚期(22～35)周利用美国ADEZA公司生产的fFN测定试剂盒,用酶联免疫吸附(ELISA)法对100例有先兆早产征、早产史及多胎孕妇进行测定。追踪病例结果进行分析。结果:100例病例中进行超声宫颈检测其中宫颈机能不全38例,早产实际发生15例(39.5%),其中9例经环扎处理,早产实际发生2例(22.2%)。fFN测定,测试结果阳性36例,其中早产实际发生31例(86.1%)。二者联合后阳性早产发生率是92.9%,有显著提高。结论:超声宫颈检测预测早产后,进行宫颈环扎可有效降低早产发生率;宫颈检测与fFN检测两者结合可提高早产预测的准确性,并有利于及时制定有效临床治疗方案。

Prediction of premature delivery by ultrasonography and fetal fibrin detection

Objective:To explore the significance of ultrasonography and fetal fibrin detection in predicting premature delivery.Methods:Fetal fibrin kit and ELISA were used to detect 100 pregnant women with premature delivery sign, premature delivery history and polyembryony during 22～35 gestational weeks.Results:Cervical incompetence and premature delivery were found in 38 and 15 women by ultrasonography, respectively 2 (22.2%) women were found premature delivery in 9 women undergoing cerclage Fetal fibrin detection was positive in 36 women, 31 women were found premature delivery Incidence of premature delivery was 92.9% by combined application of ultrasonography and fetal fibrin detection.Conclusion:Cerclage can reduce incidence of premature delivery detected by ultrasonography Ultrasonography and fetal fibrin test could improve accuracy of predicting premature delivery, in order to work out a effective treatment for premature delivery.