49例早发型重度子痫前期临床分析

目的:探讨早发型重度子痫前期的临床特点及治疗措施。方法:对山西医科大学第一临床医学院妇产科2005年1月～2008年12月收治的213例重度子痫前期患者(其中早发型49例,即24～34孕周发病者;晚发型164例,即≥34孕周发病者)及其228例新生儿进行回顾性分析,观察指标包括一般情况、并发症、合并症及母婴结局。结果:早发型重度子痫前期患者分娩孕周较晚发型早(P0.01)、治疗时间较晚发型长(P0.05),其临床症状及并发症/合并症较晚发型严重,母婴结局明显较晚发型差。结论:早发型重度子痫前期病情严重,围生儿预后不佳,应根据母胎情况,严格选择病例进行保守治疗,同时密切监测母胎病情变化。

Clinical study of 49 cases with early onset severe pre - eclampsia

Objective:To investigate the clinical features and treatment of the early onset severe preeclampsia.Methods:213 cases of patients with severe pre-eclampsia (including 49 cases of early-onset and 164 cases of late-onset ) of the First Clinical Hospital of Shanxi Medical University and their newborns were analyzed retrospectively from 2005 to 2008. The observation indicators included the general situation,complications,maternal and child outcome.Results:The Gestational age of delivery of early onset severe pre-eclampsia patients was earlier than the late-onset severe pre-eclampsia patients (P<0.01); treatment time of the former was longer than the of the latter(P<0.05).The Clinical symptoms of the former was more serious than that of the latter. The maternal and child outcome of the former was worse than that of the latter.Conclusion:Early onset severe pre-eclampsia is a serious illness,the prognos of perinatal is not good.So we should strictly select cases for conservative treatment,and closely monitor changes in maternal-fetal condition according to maternal-fetal condition.