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联合检测血糖、糖化血清蛋白在妊娠期糖筛查中的价值
引用本文:张红萍,陈益川,张德亭. 联合检测血糖、糖化血清蛋白在妊娠期糖筛查中的价值[J]. 中国妇幼保健, 2010, 25(14)
作者姓名:张红萍  陈益川  张德亭
作者单位:1. 温州医学院温州第三临床学院温州市第三人民医院·温州市妇幼保健院妇产科,浙江,温州,325000
2. 温州市妇幼保健院检验科
摘    要:目的:探讨联合检测血糖、糖化血清蛋白(GSP)在妊娠期糖代谢异常孕妇中的价值。方法:对正常妊娠组、糖筛查异常组及糖耐量异常组进行空腹葡萄糖、口服葡萄糖50g筛选,GSP测定并随访孕妇和围产儿的最终结局进行分析比较。结果:糖筛查异常组GSP(154±18)μmol/L、糖耐量异常组GSP(157±26)μmol/L,与正常妊娠组GSP(136±30)μmol/L比较,差异有统计学意义(P0.01),不同的GSP水平围产儿病率差异有统计学意义。结论:GLU、GSP联合检测在妊娠期糖筛查中有较高的临床应用价值。

关 键 词:糖化血清蛋白  糖筛查  糖耐量异常  围产儿结局

The value of glucosylated serum protein (GSP), Glucose (GLU) in glucose challenge test in pregnancy
ZHANG Hong-Ping,CHEN Yi-Chuan,ZHANG De-Ting. The value of glucosylated serum protein (GSP), Glucose (GLU) in glucose challenge test in pregnancy[J]. Maternal and Child Health Care of China, 2010, 25(14)
Authors:ZHANG Hong-Ping  CHEN Yi-Chuan  ZHANG De-Ting
Abstract:Objective:To discuss the value of glucosylated serum protein(GSP),Glucose(GLU)in diagnosing abnormal glucometabolism in pregnancy.Methods:To determine fasting blood glucose (FBG),50 g glucose challenge test(GCT),GSP in different groups including normal pregnancy,abnormal GCT pregnancy,abnormal oral glucose tolerance test(OGTT) pregnancy.The pregnant women and perinatal infants were analyzed and compared.Results:The levels of GSP in the groups of abnormal GCT pregnancy and abnormal OGTT were (154±18)μmol/L,(157±26)μmol/L respectively and significantly higher than that of normal pregnancy (136±30)μmol/L (P<0.01).Conclusion:GSP,GLU are indicators in pregnant glucometabolism abnormality screening and diagnosing.
Keywords:Glucosylated serum protein   Abnormal glucose challenge test pregnancy   Abnormal oral glucose tolerance test pregnancy   Outcome of perinatal infant
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