AECOPD阴沟肠杆菌感染特点及药物敏感性

目的了解慢性阻塞性肺病急性发作(AECOPD)阴沟肠杆菌感染的致病特点和抗生素对其敏感性。方法对106例慢性阻塞性肺病急性发作患者的临床特点、痰细菌学培养及药敏进行回顾性分析。探讨阴沟肠杆菌对老年慢性阻塞性肺病急性发作患者的致病特点以及阴沟肠杆菌的耐药特性。结果慢性阻塞性肺病急性发作阴沟肠杆菌感染,在革兰氏阴性杆菌感染中占有一定的比例,老年伴严重基础性疾病,使用多种抗生素、激素、免疫功能低下是引起阴沟肠杆菌下呼吸道感染的危险因素,其临床症状重,院内感染多见,阴沟肠杆菌对青霉素类及头孢菌素广泛耐药。结论慢性阻塞性肺病急性发作阴沟肠杆菌感染预后不良,常多重耐药,应引起临床上的重视。

The Infection Characteristics and Drug Sensitivity of Enterobacter Cloacae in Acute Exacerbations of Chronic Obstructive Pulmonary Disease

Objective To understand the infection characteristics and antibiotics sensitivity of enterobacter cloacae in acute exacerbations of chronic obstructive pulmonary disease.Methods 106 cases of patients with acute exacerbations of chronic obstructive pulmonary disease were retrospectively analyzed their clinical characteristics,sputum bacteriology cultivation and antimicrobial susceptibility.Results Patients with enterobacter cloacae in acute exacerbations of chronic obstructive pulmonary disease played a certain proportion in gram-negative bacilli infection.Elderly with serious basic diseases,multiple antibiotic,hormone,and low immune function were risk factors caused by Drain enterbacteriaceae lrti.Conclusion The infection of enterobacter cloacae in acute exacerbations of chronic obstructive pulmonary disease was poor prognosis,often multiple drug-resistant,and need more attention in clinical.