重症监护病房金黄色葡萄球菌检出率及耐药性分析

目的探讨重症监护病房(ICU)医院感染金黄色葡萄球菌(SAU)的耐药现状,为临床医师诊断与治疗提供科学依据。方法回顾性分析2010年煤炭总医院重症监护病房送检标本中金黄色葡萄球菌的检出率及其药敏结果。结果 1642例送检标本中,有269例培养出金黄色葡萄球菌(SAU),检出率为16.4%;其中甲氧西林敏感金黄色葡萄球菌(MSSA)32例占SAU总数的11.9%;甲氧西林耐药金黄色葡萄球菌(MRSA)237例占88.1%;MRSA除了对万古霉素和利奈唑胺还保持敏感外,对绝大多数抗生素都有较高的耐药率。结论 ICU中检出的SAU耐药情况日益严重。临床上SAU感染的治疗应根据实验室的药敏结果选择合适的抗菌药物。

Analysis on Test Results and Drug Resistance of Staphylococcus Aureus in Intensive Care Unit

Objective To investigate the status about detection rate and drug resistance of staphylococcus aureus(SAU) in intensive care unit(ICU).Methods We analyzed the detection rate and drug resistant data got in 2010 from ICU patients infected with SAU.Results In 1642 samples of ICU patients,SAU were positive in 269 cultured samples;the positive rate was 16.4%.Among these positive cases,32 samples(11.9%) were Methicillin Sensitive Staphylococcus Aureus(MSSA) positive;237 samples(88.1%) were Methicillin Resistant Staphylococcus Aureus(MRSA) positive.MRSA strains were only sensitive to Vancomycin and Linezolid and were almost resistant to other antibiotics.Conclusion The drug resistance of SAU from ICU patients is getting more serious.The clinical therapy of SAU infection ought to choose the appropriate antibiotics based on the results of the drug sensitive test of the laboratory.