强迫症患者临床特征与人格障碍共病状况研究

目的 探讨强迫症患者临床特征与人格障碍共病状况.方法 将91例强迫症患者设为研究组,抽取同期47名健康者设为对照组,采用Yale-Brown强迫量表、汉密顿焦虑量表和汉密顿抑郁量表评定研究组临床特征,采用<美国精神疾病诊断与统计手册>第4版中轴Ⅱ诊断用临床定式测查量表评定两组人格障碍状况.结果 71.4%的强迫症患者存在人格障碍,强迫症患者不同性别发病率差异无显著性(P＞0.05),男性发病年龄显著早于女性(P＜0.05),75.0%的患者为连续病程;研究组人格障碍临床定式测查量表评定,伴人格障碍和回避型、强迫型、消极型、抑郁型人格障碍检出率显著高于对照组(P＜0.05或0.01);不同性别和家族史的强迫症患者与人格障碍的共病率差异均无显著性(P＞0.05).结论 强迫症与人格障碍有较高的共病率,强迫症与强迫型人格障碍之间存在密切关系.

Comorbidity of clinical features and personality disorders in OCD patients

Objective To explore the comorbidity of clinical features and person-ality disorders in patients with obsessive-compulsive disorder （OCD）. Methods Ninety-one OCD patients were assigned to research group and 47 healthy persons to control group, clinical features were assessed with the Yale-Brown Obsessive Compulsive Scale （Y-BOCS）, Hamilton Anxiety Scale （HAMA） and Hamilton Depression Scale （HAMD） in research group, personality disorders of both groups with the Structured Clinical Intervener For DSM-IV axis ⅡDisorders （SCID- Ⅱ ）. Results 71.3 percent of OCD pa- tients had personality disorders, there was no gender difference in incidence of OCD （P〈0.05）, male age of onset was significantly smaller than the female （P〈0.05）, 75.0% of patients showed continous course of disease; the detection rate of comorbid, avoidant, obsessional, passive and depressive personality disor- ders was significantly higher in research than in control group （P〈0.05 or 0.01） ; there were no signifi- cant differences in comorbid rate of OCD patients with different gender and family history and personality disorders （P〈0. 05）. Conclusion OCD and personality disorders have higher comorbid rate, OCD is closely related to obsessional type of personality disorder.