家庭心理教育对精神分裂症患者服药依从性的影响

目的 探讨家庭心理教育对精神分裂症患者服药依从性的影响.方法 将122例精神分裂症患者按住院号单双号分为研究组62例和对照组60例,两组均口服利培酮治疗,研究组联合家庭心理教育.出院后随访1 a.于入组时和随访1 a末采用简明精神病量表评定精神症状,随访1 a末评定服药依从性、复发率及复住院率.结果随访1 a末,研究组脱落10例(16.1%),对照组脱落12例(20.0%),两组脱落率比较差异无显著性(χ2=0.97,P＞0.05);研究组服药依从率75.0%、复发率11.5%、复住院率9.6%,对照组分别为45.8%、31.3%、27.1%,研究组服药依从率显著高于对照组(χ2=6.67,P＜0.05),复发率、复住院率显著低于对照组(χ2=5.85、5.16,P＜0.05).入组时两组简明精神病量表总分差异无显著性(P＞0.05),随访1 a末研究组简明精神病量表总分显著低于对照组(P＜0.05).结论 家庭心理教育能显著提高患者的服药依从性,降低复发率和复住院率,对促进患者的全面康复具有重要意义.

The effect of family psycho-education on drug compliance of schizophrenics

Objective To explore the effect of family psycho-education on drug compliance of schizophren ics. Methods One hundred schizophrenics risperidone were divided into research group （n=52） and control group （n=48） according to odd or even of admission number, both groups took orally rfsperidone, research group was plus family psycho-education. They followed up for 1 years after discharge. Mental symptoms were assessed with the Brief Psychiatric Rating Scale （BPRS） at baseline and at the end of 1 year follow-up, and drug compliance, relapse rate and rehospitalization rate at the end of 1-year follow-up. Results At the end of 1-yeari＇ollow up, 10 patients（16.1%） in research group and 12 （20.0%） in control dropped out, and there was no significant difference in drop out rate （χ^2 =0.97,P〈0.05）; drug compli ance rate was significantly higher（75.0% vs 45.8%, χ^2 6.67,P〈0.05） and relapse and rehospitalization rate lower （11. 5% vs 31.3%,9.6% vs 27. 1%,χ^2 =5.85,5. 16,P〈0.05） in research than in control group. At baseline there was no significant difference in total score of the BPRS between 2 groups （P〉 0.05） and at the end of 1 year follow-up the total score of the BPRS was significantly lower in research than in control group（P〈0.05）. Conclusion The family psychoeducation could improve patients＇ drug compliance, reduce relapse and rehospitalization rate, and has significance for promoting patients＇ comprehensive rehabilitation.