| 心理因素的应激对GraVes癌患者免疫系统的影响 |
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| 引用本文： | 吴建红,田建国,臧德馨,杨海晨.心理因素的应激对GraVes癌患者免疫系统的影响[J].中国民康医学,2001,13(2):86-88. |
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| 作者姓名： | 吴建红 田建国 臧德馨 杨海晨 |
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| 作者单位： | 武汉大学人民医院 430060 |
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| 摘 要： | 目的探讨社会心理因素的应激对Graves病患者的免疫系统的影响.方法采用定式问卷,统一指导语和填表方法及有关评定量表评分,并以放射免疫法,对40例患者测定IgG、IgA、IgM及C3、C4、IL-2、I1-6与40例正常健康者对照.结果病例组IgG、IgA及IL-6显著高于正常对照组,而C3、C4及IL-2显著低于对照组.患者的抑郁分与IgG、IgA及IL-6呈明显正相关,与IL-2呈显著负相关.结论因为IgA及IL-6是疾病的危险因子,C4及IL-2是疾病的保护因子,所以社会心理因素的应激可以通过Gra-ves病患者的免疫系统而影响疾病.
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| 关 键 词： | 心理因素 Graves病 免疫系统 |
| 修稿时间： | 2000年9月27日 |
The effect of psychological stress on the immunity of patients with graves disease. |
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| WU Jianhong,TIAN Jianguo,ZANG Dexing,et al..The effect of psychological stress on the immunity of patients with graves disease.[J].medical journal of chinese peoples health,2001,13(2):86-88. |
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| Authors: | WU Jianhong TIAN Jianguo ZANG Dexing |
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| Institution: | WU Jianhong,TIAN Jianguo,ZANG Dexing,et al.The first Affiliated Hospital of HuBei Medical University,WuHan 430060 China |
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| Abstract: | Objective:To explore the effect of psychological strss on graves patients' immunity system.Methods:Using questioning and relative scales,we measured 40 patients and 40 normal people at the same time,we tested the two groups individuals serum IgG\,IgA\,IgM\,C3\,C4\,IL 2 and IL 6 by radioimmunossay.Results:The levels of serum IgG\,IgA and IL 6 in patients group were significantlhy higher than the controlled group.Furthermore,Pearson correlation analysis showed that depress scores had positive correlation with IgG\,IgA and IL 6,negative correlation with IL 2.Conclusions:Because IgA and IL 6 were risky factors,while serum C4 and IL 6 were protective factors,psychosocial stress may influnce Graves' patients with immune system. |
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| Keywords: | Psychosocial factor Graves disease Immune system |
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