常压及控制性降压下脊髓急性牵拉损伤比较研究

目的 评价控制性降压是否增加脊髓对牵拉损伤的易感性。材料与方法健康成年杂种犬6只,随机分为常压和控制性降压脊髓牵拉损伤组。观察常压及控制性降压水平下相同程度牵拉损伤后脊髓血流(SCBF)、体感诱发电位(SEP)、神经源性运动诱发电位(NMEP)改变的差异。结果 外周血有创动脉压(MABP)平均下降幅度为40．5％。经SSPS统计软件独立样本t检验,不同牵拉水平下,常压组及低压组的SCBF(％)、SEP波幅(Asep)(％)及NMEP波幅(％)无显著差异。结论 尼卡地平控制性降压不增加脊髓对牵拉损伤的易感性。

Comparison analysis of spinal cord acute distraction injury with normal blood pressure and controlled hypotension

Objective To analyse the safety of blood pressure control on spinal cord acute distraction injury.Materialsand Methods 6 healthy grown -up hybrid canines were divided into 2 groups of spinal cord distraction injury with normalblood pressure and controlled hypotension by nicardipine at random.The differences of the changes of spinal cord blood flow(SCBF), somatosensory evoked potentials (SEP) and neurogenic motor-evoked potentials (NMEP) were compared in thesetwo groups with the same distraction injury. Results Mean arterial blood pressure (MABP) decreased 40.5% by nicardip-ine. There was no significant difference among SCBF, SEP and NMEP in these two groups with the different distraction injury.Conclusion Controlled hypotension by nicardipine may not increase the susceptibility of spinal cord acute distraction injury.