我院527株优势细菌的药敏分析与合理选药

目的 :指导临床合理选用抗生素。方法 :对我院2002年1月～12月分离出的527株优势菌株进行统计分析。结果 :大肠埃希菌、铜绿假单胞菌、金黄色葡萄球菌为优势菌中常见菌 ,优势菌中G + 细菌占32 1 % ,G -细菌占67 9 %。其中 ,耐万古霉素的表皮葡萄球菌、屎肠球菌和铅黄肠球菌各1株 ,甲氧西林耐药金黄色葡萄球菌占金葡菌的64 0 % ,甲氧西林耐药表皮葡萄球菌占表葡菌的78 6 % ,甲氧西林耐药溶血性葡萄球菌占溶血性葡萄球菌的70 %。结论 :临床应了解细菌对抗生素的耐药特点 ,合理选用抗生素。

Analysis of Drug Susceptibility of 527 Strains of Dominant Bacteria and Rational Choice of Antibiotics

OBJECTIVE:To guide the rational use of antibiotics in clinical practice.METHODS:527strains of dominant bacteria,isolated in our hospital from January to December2002,were analysed.RESULTS:Escherichia coli,Pseudomonas aeruginosa,Staphylococcus aureus were the common bacteria in dominant ones.The Gram positive bacteria accounted for32.1%,and Gram-negative ones67.9%.There were one strain of Staphylococcus epidermidis,Enterococcus faecium and Enˉterococcus casselifavus resistant to Vancomycin.MRSA accounted for64.0%of Staphylococcus aureus and MRSE78.6%of Staphylococcus epidermidis.CONCLUSION:The clinical physicians should understand the characteristics of drug resistance and rationally choose the antibiotics.