| 双重滤过血浆成分分离法用于ABO血型主要不合非亲缘骨髓移植 |
| |
| 引用本文： | 黄韬,孙竞,刘俊,刘启发,孟凡义.双重滤过血浆成分分离法用于ABO血型主要不合非亲缘骨髓移植[J].第一军医大学学报,2005,25(11):1438-1440. |
| |
| 作者姓名： | 黄韬 孙竞 刘俊 刘启发 孟凡义 |
| |
| 作者单位： | [1]南方医科大学南方医院血液科,广东广州510515 [2]南方医科大学南方医院肾内科,广东广州510515 |
| |
| 摘 要： | 目的 观察双重滤过血浆成分分离法在ABO血型主要不合非亲缘骨髓移植中的疗效。方法采用双重滤过血浆成分分离法去除体内血型抗体，预防5例ABO血型主要不合非亲缘骨髓移植并发溶血反应和纯红再障。结果受者一次性双重滤过后，全部患者血型抗体均≤1：16，输注血型主要不合骨髓过程中仅1例发生轻度短暂急性溶血反应，无一例发生迟发性溶血反应和纯红再障，全部植入成功。结论双重滤过血浆成分分离法可有效预防ABO血型主要不合骨髓移植并发溶血反应和纯红再障。
|
| 关 键 词： | 双重滤过血浆成分分离 骨髓移植 ABO血型系统 血型不合 血浆交换 红细胞再生障碍 纯 溶血 |
| 文章编号： | 1000-2588（2005）11-1438-03 |
| 收稿时间： | 2005-05-22 |
Application of double-filtration plasmapheresis in major ABO-incompatible unrelated bone marrow transplantation |
| |
| HUANG Tao, SUN Jing, LIU Jun, LIU Qi-fa, MEN Fang-yi.Application of double-filtration plasmapheresis in major ABO-incompatible unrelated bone marrow transplantation[J].Journal of First Military Medical University,2005,25(11):1438-1440. |
| |
| Authors: | HUANG Tao SUN Jing LIU Jun LIU Qi-fa MEN Fang-yi |
| |
| Institution: | Department of Hematology1, Department of Nephrology2, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China |
| |
| Abstract: | OBJECTIVE: To evaluate the effect of double-filtration plasmapheresis (DFPP) in major ABO-incompatible unrelated allogenic bone marrow transplantation. METHODS: The red cell antibodies were removed by DFPP in 5 recipients to prevent hemolysis and pure red cell aplasia following major ABO-incompatible unrelated bone marrow transplantation. RESULTS: The isohemagglutinin titers of the 5 recipients were below 1:16 after DFPP with only one recipient developed transient mild acute hemolysis. Delayed hemolysis and pure red cell aplasia occurred in none of the cases and all recipients were completely engrafted. CONCLUSION: DFPP can effectively prevent hemolysis and pure red cell aplasia in recipients of unrelated bone marrow transplantation with major ABO-incompatibility. |
| |
| Keywords: | double-filtration plasmapheresis bone marrow transplantation ABO blood-group system blood group incompatibility plasma exchange red-cell aplasia pure hemolysis |
| 本文献已被 维普 等数据库收录！ |
