新生儿重度窒息的预后与血糖浓度关系分析

目的研究重度窒息新生儿的预后与血糖浓度的关系，为调节血糖浓度及判定预后提供依据。方法对92例重度窒息新生儿在治疗前后测定其血糖浓度，根据不同的血糖浓度将治疗前后的血糖分为低值组、正常组和高值组，分析各组的后遗症及死亡数，统计其差异性。结果重度窒息新生儿在治疗前血糖与预后关系上总的构成比上存在差异，低值组与正常组、低值组与高值组间有显著差异，而正常组与高值组间无显著差异。治疗后血糖与预后关系上总的构成比存在显著差异。低值组与正常组间、正常组与高值组间有显著差异；低值组与高值组间差异无显著性。治疗前后低值组、正常组、高值组三组间的治愈人数比较：治疗前后低值组间及高值组间治愈人数与未治愈人数间有显著差异而正常组间治愈人数与未治愈人数比较无差异。结论新生儿重度窒息无论治疗前后低血糖都对预后有不良影响，而治疗前高血糖对新生儿重度窒息预后无影响，治疗后血糖仍高者对预后有不良影响；治疗前后的高血糖对预后的影响有差异性。新生儿重度窒息治疗时应严格控制葡萄糖的输注，并随时监测血糖，以免血糖异常的发生特别是治疗后引起的高血糖。

Analysis of the relation between the prognosis of neonatal asphyxia and the level of bleed glucose

Objective To investigate the relation between the prognosis of neonatal asphyxia and the level of blood glucose and provide the basis for the adjustment of blood glucose and the determination of prognosis. Methods Blood glucose before and after treatment was determined in 92 cases of neonatal asphyxia. The patients were divided into low, normal and high groups according to the level of blood glucose. Differences in sequelae and fatality among groups were compared. Results Before treatment the relations between the level of blood glucose and the prognosis showed significant differences in the low VS normal group and the low VS high group. After treatment, the relations between the level of blood glucose and the prognosis showed significant differences in the low VS normal group and normal VS the high group. The data before and after treatment in each group was combined respectively and further compared. Significant differences were found in the beth low VS both high group, but not in the both low VS beth normal group. Conclusion Poor prognosis is indicated in asphyxiated neonate with low blood glucose. Hyperglycemia shows different outcomes in prognosis, i.e. before treatment hyperglycemia does not show influence on prognosis, after treatment hyperglycemia shows adverse influence on prognosis. Therefore blood glucose should be strictly controlled and monitored in the treatment of neonatal asphyxia patients to avoid hyperglycemia.